UJI KARAKTERISTIK FISIK FORMULASI CLAY MASK EKSTRAK ETANOL DAUN UNGU (Graptophyllum pictum L.Griff) DAN UJI AKTIVITAS ANTIBAKTERI TERHADAP Staphylococcus aureus

Choirun Nisak; Hasriyani Hasriyani; Bintari Tri Sukoharjanti

doi:10.59003/nhj.v5i2.1534

Authors

Choirun Nisak Universitas Muhammadiyah Kudus
Hasriyani Hasriyani Universitas Muhammadiyah Kudus
Bintari Tri Sukoharjanti Universitas Muhammadiyah Kudus

DOI:

https://doi.org/10.59003/nhj.v5i2.1534

Keywords:

Clay mask, purple leaves, Staphylococcus aureus, antibacterial activity, physical characteristics

Abstract

Skin problems caused by hormones, dead skin cells, clogged pores due to excess oil, and bacterial infections such as Staphylococcus aureus are known as acne. Antibiotics can cause side effects, so natural alternatives such as purple leaf masks are used because of their content of flavonoids, saponins, and tannins with antibacterial properties. Clay masks work by absorbing oil and cleaning pores. This study aims to determine the effectiveness of purple leaf extract clay mask in inhibiting Staphylococcus aureus and its physical characteristics. Formulations include F0 (0%), F1 (20%), F2 (23%), and F3 (26%) with antibacterial testing using disc diffusion methods and physical characteristics. The best physical results are shown by F2 (23%) because the physical quality of the formula is the best. Antibacterial results showed that F3 (26%) had the largest inhibition zone (9.16 mm), followed by F2 (5.76 mm), and F1 (3.9 mm). Purple leaf clay mask shows potential as an antibacterial against Staphylococcus aureus with F2 (23%) considered the best formulation due to its good inhibitory effect and standard-compliant physical properties.

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References

Abdilah, F., & Kurniawan, K. (2022). Morphological Characteristics of Air Bacteria in Mannitol Salt Agar Medium. Borneo Journal of Medical Laboratory Technology, 5 (1), 353-359. https://doi.org/10.33084/bjmlt.v5i1.4438

Andi, H., & Rivai, R. (2021). Ekstraksi Uji Aktivitas Daun Ungu (Graptophyllum pictum L.Griff) terhadap Staphylococcus aureus. Jurnal Kesehatan Yamasi Makassar, 5 (1), 45–49.

Asthyananda, M., Tinggi, S., & Kesehatan, I. (2024). Formulasi Clay Mask Daun Binahong ( Anredera Cordifolia (Ten.) Steenis) dan Uji Inhibisi Staphylococcus aureus Formulation of Clay Mask of Binahong Leaf (Anredera Cordifolia (Ten.) Steenis) and Inhibition Test of Staphylococcus aureus. 9 (2), 105–114. https://doi.org/10.26874/kjif.v9i2.680

Diyanati, A., & Marliana, E. (2023). Formulasi dan Evaluasi Fisik Sediaan Clay Mask Ekstrak Daun Kelor (Moringa oleifera L.). Prosiding Seminar Nasional Diseminasi Penelitian, 3.

Fadel, N. M., Huda, N., Hasriyani, Besan, J. E., & Ayuningsih, S. (2024). Aktivitas Antibakteri Ekstrak Etanol Daun Parijoto (Medinila Speciosa Blume) Pada Sediaan Gel Hand Sanitizer. 9, 1–12.

Fauziah, F., Alvanny, N., & Andalia, K. (2022). Evaluasi Formulasi Masker Clay Dari Ekstrak Etanol Daun Pepaya (Carica Papaya L.) Sebagai Anti Jerawat. Jurnal Riset Kefarmasian Indonesia, 4 (3), 306–320. https://doi.org/10.33759/jrki.v4i3.283

Hafizah, Q., Permatasari, L., & Rachmalia Izzatul Muchlishah, N. (2024). Faktor - Faktor Yang Mempengaruhi Aktivitas Antibakteri Daun Mangrove (Rhizophora mucronata) Terhadap Bakteri Staphylococcus aureus. Jurnal Kesehatan Tambusai, 5 (2), 3833–3834.

Lasmini, T., Saphira, A., Dos Marliana, L. B., & Sherly Margaretta, T. (2022). Identifikasi Bakteri Staphylococcus aureus Pada Swab Rongga Hidung Penjamah Makanan Di Jalan Durian Kota Pekanbaru. Prosaiding AIPLMI, 5, 281–292. https://prosiding.aiptlmi-iasmlt.id/index.php/prosiding/article/view/60/25

Mandiri, J. S., Tuloli, T. S., Asriastuti, A. N., Dwifrila, D., Gubali, R., Rombe, N. T., Kartika, P., Kahar, A., & Tolulu, S. N. (2024). Gambaran Frekuensi Penggunaan Antimikroba Oral Pada Tatalaksana Terapi Pasien Acne Vulgaris Di Rsud Toto Kabila. 19 (1), 25–35.

Maulida, Y., & Topik, M. M. (2024). Penanganan Acne Vulgaris Terkini. Jurnal Ilmiah Ilmu Kesehatan Dan Kedokteran, 2 (3), 98–111.

Nugraha, P. Y., Sri, E., Astuti, Y., & Molin, N. M. (2024). Pengaruh ekstrak daun ungu ( Graptophyllum pictum L. Griff ) terhadap pertumbuhan bakteri streptococcus sobrinus pada karies gigi anak. 886–895.

Purba, A. U. C., Naliani, S., & Sugiaman, V. K. (2023). Efektivitas Antibakteri Fraksi Buah Merah (Pandanus conoideus Lam) sebagai Pembersih Gigi Tiruan Sebagian Lepasan terhadap Staphylococcus aureus. E-GiGi, 11 (2), 143–151. https://doi.org/10.35790/eg.v11i2.44464

Putri, C. N., Qornain, W. D., Bamahri, F., Yuliastuti, G. E., & Kurniawan, M. (2024). Klasifikasi Jenis Jerawat pada Data Citra Jerawat Wajah Menggunakan Convolutional Neural Network. TIN: Terapan Informatika Nusantara, 5 (2), 172–181. https://doi.org/10.47065/tin.v5i2.5231

Putri Novianti, E., & Wirnawati, W. (2024). Formulasi Sediaan Krim Anti Jerawat Ekstrak Etanol Daun Sungkai (Peronema Canescens Jack) dan Uji Aktivitas terhadap Bakteri Propionibacterium acnes dan Staphylococcus aureus. Jurnal Global Ilmiah, 1 (10). https://doi.org/10.55324/jgi.v1i10.104

Rahmawati, R. P., Anggun, L., Primandana, A. Z., & Dwiyanti, U. (2021). Pengaruh Pemberian Ekstrak Etanol 96% Daun Suruhan (Peperonia Pellucida (L.) Kunth) Terhadap Pertumbuhan Bakteri Propionibacterium acnes Dengan Metode Difusi Cakram. Indonesia Jurnal Farmasi, 6 (1), 22. https://doi.org/10.26751/ijf.v6i1.1196

Saerang, M. F., Edy, H. J., & Siampa, J. P. (2023). Formulasi Sediaan Krim Dengan Ekstrak Etanol Daun Gedi Hijau (Abelmoschus Manihot L.) Terhadap Propionibacterium acnes. Pharmacon, 12 (3), 350–357. https://doi.org/10.35799/pha.12.2023.49075

Sari, P. I., Suleman, A. W., & Patti, S. (2024). Formulasi Dan Uji Aktivitas Antibakteri Clay Mask Kombinasi Daun Pegagan ( Centella Asiatica L ) Dan Daun Afrika ( Vernonisa Amygdalina Del) Terhadap Staphylococcus aureus. Jurnal Kesehatan Tambusai, 5 (1), 2002–2016.

Sartika, S., & Indradi, R. B. (2021). Berbagai Aktivitas Farmakologi Tanaman Daun Ungu (Graptophyllum pictum L. Griff). Indonesian Journal of Biological Pharmacy, 1 (2), 88. https://doi.org/10.24198/ijbp.v1i2.37531

Syahrani, N., Kurniawati, A., Prihanti, A. M., Sulistyani, E., & Lestari, P. E. (2024). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Ungu (Graptophyllum pictum (L) Griff) terhadap Pertumbuhan Streptococcus sanguinis. Pustaka Kesehatan, 12 (1), 19. https://doi.org/10.19184/pk.v12i1.42325

Wally, P., Marwah, A. S., & Azril Fajar Warang. (2022). Efektivitas Ekstrak Myristica fragrans Houtt terhadap Bakteri Patogen Pseudomonas aeruginosa dan Methicilin Resistensi Staphylococcus aureus. Jurnal Biotek, 10 (2), 224–239. https://doi.org/10.24252/jb.v10i2.31930

Wati, I. R., Rahayu, T. P., & Fitriyati, L. (2023). Formulasi Dan Uji Aktivitas Antibakteri Sediaan Masker Clay Ekstrak Metanol Daun Mangga Arum Manis (Mangifera indica L.) terhadap Propionibacterium acnes. Jurnal Farmasi Klinik Dan Sains, 3 (1), 26. https://doi.org/10.26753/jfks.v3i1.965

Windria, S., Cahyaningtyas, A. A., Cahyadi, A. I., Wiraswati, H. L., & Ramadhanti, J. (2023). Identifikasi Fenotip dan Genotip Staphylococcus aureus Isolat Asal Susu Sapi Perah Mastitis Subklinis di Wilayah Pamulihan, Kabupaten Sumedang Jawa Barat. Jurnal Sain Veteriner, 41 (2), 215. https://doi.org/10.22146/jsv.76052

Yanto, R. B., Satriawan, N. E., & Suryani, A. (2021). Identifikasi Dan Uji Resistensi Staphylococcus aureus Terhadap Antibiotik (Chloramphenicol dan Cefotaxime Sodium) dari Pus Infeksi Piogenik Di Puskesmas Proppo. Jurnal Kimia Riset, 6 (2), 154. https://doi.org/10.20473/jkr.v6i2.30694

Yasintha, A. A., & Makkiyah, F. A. (2023). Aktivitas Antioksidan dan Antiinflamasi pada Daun Ungu ( Graptophyllum pictum ). Ikraith-Humainora, 8 (1), 177–187.