EFEKTIFITAS PEMBERIAN SUSU KAMBING FERMENTASI TERHADAP ANTROPOMETRI BAYI BARU LAHIR

Ira Suryanis; Hasmiwati Hasmiwati; Nur Indrawaty Lipoeto; Novirman Jamarun

doi:10.59003/nhj.v5i7.1834

Authors

Ira Suryanis Universitas Biturrahmah dan Universitas Andalas
Hasmiwati Hasmiwati Universitas Andalas
Nur Indrawaty Lipoeto Universitas Andalas
Novirman Jamarun Universitas Andalas

DOI:

https://doi.org/10.59003/nhj.v5i7.1834

Keywords:

Fermented goat milk, infant anthropometry

Abstract

The balance of the gut microbiota during pregnancy is essential for maintaining maternal health and supporting optimal fetal development. Fermented goat’s milk contains naturally occurring probiotics that contribute to microbiota homeostasis and improved maternal nutritional status. This study aimed to evaluate the effect of fermented goat’s milk consumption on newborn anthropometric outcomes. Two group pretest posttest control was applied involving 15 third-trimester pregnant women who met the inclusion criteria. Participants consumed 75 mL of fermented goat’s milk daily for a period of 9–12 weeks. Maternal characteristics and neonatal anthropometric parameters were collected through structured observations and questionnaires. Data were analyzed using paired statistical tests. The findings demonstrated statistically significant improvements (p < 0.05) in neonatal birth weight, body length, and head circumference following the intervention. These results indicate that fermented goat’s milk may positively influence fetal growth without inducing gut microbiota dysbiosis. Further studies employing controlled designs and larger sample sizes are warranted to confirm these findings and elucidate the underlying mechanisms.

Downloads

Download data is not yet available.

References

Amir, M., Brown, J. A., Rager, S. L., Sanidad, K. Z., Ananthanarayanan, A., & Zeng, M. Y. (2020). Maternal microbiome and infections in pregnancy. In Microorganisms(Vol.8,Issue12,pp.1–21).MDPIAG. https://doi.org/10.3390/microorganisms8121996

Nuriel-Ohayon, M., Neuman, H., Ziv, O., Belogolovski, A., Barsheshet, Y., Bloch, N., et al. (2019a). Progesterone Increases Bifidobacterium Relative Abundance during Late Pregnancy. Cell Reports, 27(3), 730-736.e3. https://doi.org/10.1016/j.celrep.2019.03.075

Koren, O., Goodrich, J. K., Cullender, T. C., Spor, A., Laitinen, K., Kling Bäckhed, H., et al. (2012). Host remodeling of the gut microbiome and metabolic changes during pregnancy. Cell, 150(3), 470–480. https://doi.org/10.1016/j.cell.2012.07.008

Marlicz, W., Yung, D. E., Skonieczna-żydecka, K., Loniewski, I., van Hemert, S., Loniewska, B., & Koulaouzidis, A. (2017). From clinical uncertainties to precision medicine: The emerging role of the gut barrier and microbiome in small bowel functional diseases. In Expert Review of Gastroenterology and Hepatology (Vol. 11, Issue 10, pp. 961–978). Taylor and Francis Ltd.https://doi.org/10.1080/17474124.2017.1343664

Figuero, E., Han, Y. W., & Furuichi, Y. (2020). Periodontal diseases and adverse pregnancy outcomes: Mechanisms. In Periodontology 2000 (Vol. 83, Issue 1, pp. 175–188). Blackwell Munksgaard. https://doi.org/10.1111/prd.12295

Rapone, B., Ferrara, E., Montemurro, N., Converti, I., Loverro, M., Loverro, M. T., et al. (2020). Oral microbiome and preterm birth: Correlation or coincidence? A narrative review. In Open Access Macedonian Journal of Medical Sciences (Vol. 8, Issue F, pp. 123–132). Open Access Macedonian Journal of Medical Sciences. https://doi.org/10.3889/oamjms.2020.4444

Baldassarre, M. E., Palladino, V., Amoruso, A., Pindinelli, S., Mastromarino, P., Fanelli, M., et al (2018). Rationale of probiotic supplementation during pregnancy and neonatal period. In Nutrients (Vol. 10, Issue 11). MDPI AG. https://doi.org/10.3390/nu10111693

Buggio, L., Somigliana, E., Borghi, A., & Vercellini, P. (2019a). Probiotics and vaginal microecology: Fact or fancy? In BMC Women’s Health (Vol. 19, Issue 1). BioMed Central Ltd. https://doi.org/10.1186/s12905-019-0723-4

Jarde, A., Lewis-Mikhael, A. M., Moayyedi, P., Stearns, J. C., Collins, S. M., Beyene, J., & McDonald, S. D. (2018). Pregnancy outcomes in women taking probiotics or prebiotics:A systematic review and meta-analysis. BMC Pregnancy and Childbirth, 18(1). https://doi.org/10.1186/s12884-017-1629-5

Othman, M., Neilson, J. P., & Alfirevic, Z. (2007). Probiotics for preventing preterm labour. In Cochrane Database of Systematic Reviews (Issue 1). John Wiley and Sons Ltd. https://doi.org/10.1002/14651858.CD005941.pub2

Hiltunen, H., Collado, M. C., Ollila, H., Kolari, T., Tölkkö, S., Isolauri, E., Salminen, S., & Rautava, S. (2022). Spontaneous preterm delivery is reflected in both early neonatal and maternal gut mikrobiota. Pediatric Research, 91(7), 1804–1811. https://doi.org/10.1038/s41390-021-01663-8

Rackaityte, E., Halkias, J., Fukui, E. M., Mendoza, V. F., Hayzelden, C., Crawford, E. D., et al (2020). Viable bacterial colonization is highly limited in the human intestine in utero. Nature Medicine, 26(4), 599–607. https://doi.org/10.1038/s41591-020-0761-3

Younge, N., McCann, J. R., Ballard, J., Plunkett, C., Akhtar, S., Araújo-Pérez, F., et al. (2019). Fetal exposure to the maternal mikrobiota in humans and mice. JCI Insight, 4(19).

https://doi.org/10.1172/jci.insight.127806

Soltani, H., Lipoeto, N. I., Fair, F. J., Kilner, K., & Yusrawati, Y. (2017). Pre-pregnancy body mass index and gestational weight gain and their effects on pregnancy and birth outcomes: A cohort study in West Sumatra, Indonesia. BMC Women’s Health, 17(1). https://doi.org/10.1186/s12905-017-0455-2

Wang Xinzhou, Peng Zhang, X. Z. (2021). Probiotics Regulate Gut Mikrobiota : An Effective Method to Improve Immunity. Molecules, 26, 6076, 1–15.

Kim, C. J., Romero, R., Chaemsaithong, P., & Kim, J. S. (2015). Chronic inflammation of the placenta: Definition, classification, pathogenesis, and clinical significance. In American Journal of Obstetrics and Gynecology (Vol. 213, Issue 4, pp. S53–S69). Mosby Inc. https://doi.org/10.1016/j.ajog.2015.08.041

Morales, P., Fujio, S., Navarrete, P., Ugalde, J. A., Magne, F., Carrasco-Pozo, C., et al (2016). Impact of Dietary Lipids on Colonic Function and Mikrobiota: An Experimental Approach Involving Orlistat-Induced Fat Malabsorption in Human Volunteers. Clinical and Translational Gastroenterology, 7(4), e161.https://doi.org/10.1038/ctg.2016.20

Wang Xinzhou, Peng Zhang, X. Z. (2021). Probiotics Regulate Gut Mikrobiota : An Effective Method to Improve Immunity. Molecules, 26, 6076, 1–15.

Yang, H., Guo, R., Li, S., Liang, F., Tian, C., Zhao, X., Long, Y., et al (2020). Systematic analysis of gut mikrobiota in pregnant women and its correlations with individual heterogeneity. Npj Biofilms and Microbiomes, 6(1). https://doi.org/10.1038/s41522-020-00142-y

Chen, Y., Li, Z., Tye, K. D., Luo, H., Tang, X., Liao, Y., et al.(2019). Probiotic supplementation during human pregnancy affects the gut mikrobiota and immune status. Frontiers in Cellular andInfectionMicrobiology, 9(JUL).

https://doi.org/10.3389/fcimb.2019.00254