ANGINA PECTORIS TIDAK STABIL (UAP)
DOI:
https://doi.org/10.59003/nhj.v5i7.1797Keywords:
Tuberculosis, Tuberculosis in children, TB in children, Diagnosis, Risk factors, BCG vaccination, Prevention, Clinical manifestations.Abstract
Unstable Angina Pectoris (UAP) is a form of acute coronary syndrome characterized by new-onset chest pain, worsening angina, or symptoms occurring at rest without elevation of cardiac biomarkers. This condition reflects unstable myocardial ischemia and requires prompt management to prevent progression to myocardial infarction. The diagnosis of UAP is established through a combination of clinical symptoms and electrocardiographic findings such as transient ST-segment depression, T-wave inversion, or other ischemic changes, accompanied by normal troponin levels. Initial management includes the administration of antiplatelet agents, anticoagulants, nitrates, beta-blockers, and statins according to current guidelines, along with risk stratification to determine the need for invasive intervention. Further evaluation through coronary angiography is essential to assess the degree of coronary artery stenosis and guide subsequent treatment strategies, whether through percutaneous coronary intervention or intensive medical therapy. Early identification, comprehensive evaluation, and evidence-based intervention are crucial to reducing morbidity and preventing more severe cardiovascular complications in patients with UAP.
Downloads
References
Al Rahmad AH. Hubungan Indeks Massa Tubuh dengan Kolesterol, LDL, dan Trigliserida pada Pasien Jantung Koroner di Kota Banda Aceh. Jurnal Kesehatan. 2021;9(1):1-8. doi:10.25047/j-kes.v9i1
American Heart Association. Global Cardiovaskular Disease Statistics . Heart Disease and Stroke Statistics Update 2024. Published online 2024.
Amisi WG, Nelwan JE, Kolibu FK. Hubungan antara Hipertensi dengan Kejadian Penyakit Jantung Koroner pada Pasien yang Berobat di Rumah Sakit Umum Pusat Prof. Dr. R. D. Kandou Manado. Jurnal Kesmas. 7(4).
Badan Penelitian dan Pengembangan Kesehatan Kementerian Kesehatan RI. Hasil Riskesdas 2013. Published online 2013.
Byrne RA, Rossello X, Coughlan. 2023 ESC Guidelines for the Management of Acute Coronary Syndromes. European Heart Journal; 2023.
Char. The Patophysiology of Acute Coronary Syndromes. Journal Emergency Medicine Cardiac Research . 2005;1(1):1-6.
Csige I, Ujvarosy D, Szabo Z, Paragh G. The Impact of Obesity on the Cardiovascular System. J Diabetes Res. Published online 2018. doi:10.1155/2018/3407306
Endah R, Patriyani H, Ferry D, et al. Faktor Dominan Risiko Terjadinya Penyakit Jantung Koroner (PJK). Jurnal Keperawatan Global. 2016;1(1):01-54.
Ghani L, Novriani H, Susilawati MD. Faktor Risiko Dominan Penyakit Jantung Koroner di Indonesia. Buletin Penelitian Kesehatan . 2016;44(3):153-164.
Goyal A, Zeltser R, Gunn A. Unstable Angina. National Library of Medicine. Published online September 18, 2022.
Hajar R. Risk Factors for Coronary Artery Disease: Historical Perspectives. Heart Views. 2017;18(3):109-114.
Halimuddin, H. Lokasi Infark dengan kejadian Acute Kidney Injury pada Pasien dengan STEMI. Jurnal Keperawatan. 2022;10(1)
Juzar DA, Sungkar S, Firman D. Pedoman Tata Laksana Sindrom Koroner Akut. 5th ed. Perhimpunan Dokter Spesialis Kardiovaskular Indonesia (PERKI); 2024.
Lilly L. Pathophysiology of Heart Disease : A Collaborative Project of Medical Students and Faculty. 5th ed. Harvard Medical School.
M. Hattu D, Weraman P, L.H.Folamauk C. Hubungan Merokok dengan Penyakit Jantung Koroner di RSUD Prof. DR. W. Z. Johannes Kupang. Timorese Journal of Public Health. 2020;1(4).
Majid A. Penyakit Jantung Koroner : Patofisiologi, Pencegahan, Dan Pengobatan Terkini.; 2018.
Neumann FJ, Sechtem U, Banning AP, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. Eur Heart J. 2020;41(3):407-477. doi:10.1093/eurheartj/ehz425
Nofita Nengsih. Peran Olahraga Terhadap Penyakit Jantung. Jurnal Kesehatan dan Kedokteran. Published online 2020.
Perhimpunan Dokter Spesialis Kardiovaskular Indonesia. Panduan Prevensi Penyakit Kardiovaskular Aterosklerosis. Published online 2022.
Profil Kesehatan Provinsi Sumatera Barat 2016.
Rilantono LI, Baraas F, Karo S, Roebiono PS. Buku Ajar Kardiologi . Fakultas Kedokteran Universitas Indonesia; 2024.
Santosa WN, Baharuddin. Penyakit Jantung Koroner dan Antioksidan. KELUWIH: Jurnal Kesehatan dan Kedokteran. 2020;1(2):98-103. doi:10.24123/kesdok.v1i2.2566
Setiadi. Buku Ajar Ilmu Penyakit Dalam Jilid 2. Internal Publishing; 2015.
Shulifah R. Hubungan Faktor Resiko dan Karakteristik Penderita dengan Kejadian Penyakin Jantung Koroner. Jurnal Mahakam . 2016;1(1):17-26.
Stergiopoulus K, Brown DL. Evidence-Based Cardiology Consult. Springer
Usman Y, Iriawan RW, Rosita T, et al. Indonesia’s sample registration system in 2018: A work in progress. Journal of Population and Social Studies. 2018;27(1):39-52. doi:10.25133/JPSSV27N1.003
Usnizar F, Novriyanti ID, Irwan. Pengaruh Lama Hipertensi Terhadap Penyakit Jantung Koroner di Poliklinik Kardiologi RSUP. Dr. Mohammad Hoesin Palembang 2012. Jurnal Kedokteran dan Kesehatan. 2014;1(1):55-60.
WHO. Cardiovascular Disease Risk Factor.
Xu J, Murphy SL, Kochanek KD, Arias E. Mortality in the United States, 2021. Published online December 2022.
Yulanda G, Lisiswanti R. Penatalaksanaan Hipertensi Primer. Majority. 2017;6(1).
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Boy Hutaperi
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
NHJ is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Articles in this journal are Open Access articles published under the Creative Commons CC BY-NC-SA License This license permits use, distribution and reproduction in any medium for non-commercial purposes only, provided the original work and source is properly cited.
Any derivative of the original must be distributed under the same license as the original.
