FORMULASI DAN UJI EFEKTIVITAS SEDIAAN ROLL ON AROMATERAPI BERBAHAN AKTIF MINYAK ATSIRI DAUN JERUK NIPIS (Citrus aurantifolia) SEBAGAI RELAKSASI PADA KELINCI ANGGORA (Oryctolagus cuniculus domesticus)
DOI:
https://doi.org/10.59003/nhj.v5i2.1550Keywords:
antistress, aromatherapy roll-on, Angora rabbits, lime leaf (Citrus aurantifolia)Abstract
Anxiety disorder is a mental condition characterized by excessive feelings of fear and worry. Individuals experiencing this disorder may feel anxious almost constantly, which can interfere with their daily lives. Aromatherapy is a therapeutic practice that utilizes essential oils extracted from plant parts—typically through distillation—to enhance physical and emotional well-being. The development of aromatherapy as a treatment can be applied to roll-on formulations due to their convenient and practical use, aligning with public preference. This study aims to evaluate the physical quality and effectiveness of an aromatherapy roll-on preparation containing lime leaf (Citrus aurantifolia) essential oil for relaxation in Angora rabbits (Oryctolagus cuniculus domesticus). Physical quality assessments included homogeneity test, organoleptic evaluation, pH measurement, user preference test, and skin irritation test. Effectiveness testing was conducted based on varying concentrations (3%, 4%, 5%) and a control group. The collected data were processed using SPSS software, applying a one-way ANOVA. The findings revealed that all preparations were yellow liquids with the distinctive citrus aroma of lime essential oil. Homogeneity and pH tests confirmed that all formulations met the criteria for topical application. In terms of effectiveness, the 5% concentration yielded the most optimal results. Normality and homogeneity tests indicated that all data sets had normal and homogeneous distributions (p>0,05), fulfilling requirements for ANOVA. The ANOVA results showed a significant difference among the five treatment groups (p<0,05). Post Hoc analysis identified a significant difference between the negative control group and all other treatment groups (p<0,05).
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References
Abdullah, D., Amelia, R., Dewi, N. P., & Tetivani, A. (2024). Efek Pemberian Lilin Aromaterapi Pada Pengobatan Gangguan Cemas. Journal of Psychology, 1(1), 21–32. https://journal.ppmi.web.id/index.php/jp/article/view/1208
Caroline, I. R. (2022). Efektivitas Penggunaan Minyak Atsiri Sebagai Aromaterapi. Jurnal Farmasi dan Kesehatan, 11(2), 263–275. https://doi.org/https://doi.org/10.48191/medfarm.v11i2.101
Chusniah, I., & Muhtadi, A. (2017). Aktivitas Jeruk Nipis (Citrus aurantifolia) Sebagai Antibakteri, Antivirus, Antifungal, Larvasida, dan Anthelmintik. Farmaka, 15(2), 9–22.
Ermawati, N. (2018). Uji Iritasi Sediaan Gel Antijerawat Fraksi Larut Etil Asetat Ekstrak Etanol Daun Binahong (Anredera cordiofolia (Ten.) Steenis) Pada Kelinci. Jurnal Pena, 32(2), 33–37. https://doi.org/https://doi.org/10.31941/jurnalpena.v32i2.804
Pratasik, M. C. M., Yamlean, P. V. Y., & Wiyono, W. I. (2019). Formulasi dan Uji Stabilitas Fisik Sediaan Krim Ekstrak Etanol Daun Sesewanua (Clerodendron squamatum Vahl.). Pharmacon, 8(2), 261–267. https://doi.org/10.35799/pha.8.2019.29289
Rahmawati, R. P., Setyaningrum, I., Arif, F., & Alviona, J. Della. (2024). Perbandingan Formula Ekstrak Minyak Atsiri Daun Kemangi (Ocimum Basilicum L) Terhadap Uji Sifat Fisik Sediaan Lilin Aromaterapi. Indonesia Jurnal Farmasi, 9(1), 13–19. https://doi.org/https://doi.org/10.26751/ijf.v9i1.2446
Rasyadi, Y., Yesika, R., Handayani, F. S., & Hanifa, D. (2024). Tes Iritasi Roll On Aromaterapi Minyak Atsiri Kulit Jeruk Kasturi (Citrus microcarpa Bunge). Parapemikir, 13(2), 211–215. https://doi.org/10.30591/pjif.v13i2.6703
Rizqi, J., Amestiasih, T., & Rahmadani, I. F. (2024). Formulasi Dan Evaluasi Organoleptik Minyak Atsiri Jeruk Nipis sebagai Sediaan Aromaterapi. Media Informasi, 20(2), 67–72. https://doi.org/https://doi.org/10.37160/mijournal.v20i2.634
Sianturi, R. (2022). Uji Homogenitas Sebagai Syarat Pengujian Analisis. Jurnal Pendidikan Sains Sosial dan Agama, 8(1), 386–397. https://doi.org/10.53565/pssa.v8i1.507
Suryani, I., Meilina, R., Hafizhathifa, F., Astryna, S. Y., & Safitri, F. (2024). Formulasi Dan Evaluasi Sediaan Roll-On Aromaterapi Minyak Atsiri Pala (Myristica fragrans houtt.) Dan Serai (Cybopongon citratus) Sebagai Antiemetik. Journal of healthcare Technology and Medicine, 10(1), 1–10. https://doi.org/https://doi.org/10.33143/jhtm.v10i1.4215
Watung, E. J., Maarisit, W., Sambou, C. N., & Kanter, J. W. (2020). Uji Efektivitas Sediaan Gel Ekstrak Batang Pepaya (Carica papaya L.) Sebagai Penyembuh Luka Sayat Pada Tikus Putih (Rattus novergicus). Jurnal Biofarmasetikal Tropis, 3(2), 1–7. https://doi.org/10.55724/j.biofar.trop.v3i2.278
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