POTENSI PROBIOTIK DADIAH TERHADAP KADAR KOLESTEROLTOTAL TIKUS PUTIH JANTAN  GALUR WISTAR (RATTUS NORVEGICUS)

Evasha  SA; Dessy Abdullah; Aryaldy  Zulkarnaini

Authors

Evasha SA Universitas Baiturrahmah
Dessy Abdullah Universitas Baiturrahmah
Aryaldy Zulkarnaini Universitas Baiturrahmah

Keywords:

Blood Sugar, Dadiah Probiotic, white male rats (Rattus norvegicus), Total Cholesterol

Abstract

Dadiah is a fermented buffalo milk product from traditional food. The positive impact of probiotics in humans increases resistance in the digestive system. It lowers cholesterol—this study aimed at the effect of probiotics on total cholesterol levels in white male rats. The research method used a true experiment with a post-test randomized control group design. The sample used Wistar strain male white rats (Rattus norvegicus) aged 8-12 weeks and weighing 250-300 grams. Samples were taken in four groups randomly with 28 rats—processing using One Way ANOVA and LSD. The mean total cholesterol levels in rats (K +) were 100.85 mg /dL. (K-), namely 205.28 mg / dL Group P1 and P2, namely 170.28 mg / dL and 158.28 mg / dL. The largest decrease in cholesterol levels compared to (K +) was in the P2 group. The mean blood sugar levels in the group (K +) 85.71 mg / Dl, (K-), at P1 curd was 1.87g, namely 87 mg / dL, and at P2 curds 3.74 g was 102.71 mg / dL. The greatest decrease in cholesterol levels compared to (K +) was at P1. There was an effect of curd probiotic on total cholesterol levels of white male rats with (P <0.05). The conclusion was that curd probiotic's effect on total cholesterol levels of white male rats.

Downloads

Download data is not yet available.

References

Firdaini. Pengaruh Probiotik Dadih Terhadap Kadar Kolesterol LDL Pada Tikus Jantan Galur Wistar Model Hiperkolesterolemia. Fakultas Kedokteran Universitas Andalas Padang; 2016.

Fitri Rr. Hubungan Asupan Lemak, Kolesterol Dan Status Gizi Dengan Kadar Kolesterol Pasien Hiperkolesterolemia Rawat Jalan Di Rsud Dr. Moewardi Surakarta. 2019;1–119.

Ganesha IG. Probiotik. Faculty Of Medicine Udayana; 2016.

Khalid K. An Overview of Lactid Acid Bacteria. International Journal Of Biosciences; 1 ; 1-13; 2016.

Melia et al.. Characterization of the Antimicrobial Activity of Lactic Acid Bacteria Isolated from Buffalo Milk in West Sumatera (Indonesia) Against Listeria monocytogenes. Pakistan Journal of Nutrition. ISSN 1680-5194 DOI:10.3923/pjn ; 2017. P. 645.650.

Murray et al. Biokimia harper 27 Edisi. Buku Kedokteran Jakarta.

Pamungkas T. Efek Ekstrak Daun Sukun (Artocarpus altilis) Dalam Menurunkan Kadar Kolesterol Total Tikus Putih (Rattus norvegicus). Fakultas Kedokteran Universitas Muhammadiah Malang; 2015.

Pratama P. Pengaruh Pemberian Kefir Susu Sapi Terhadap Kadar Kolesterol LDL Tikus Jantan Sprague Dawley Hiperkolesterolemia. Universitas Dipenegoro; 2012.

Rini Tp, Karim Dan R.Novayelinda. Gambaran Kadar Kolesterol Pasien Yang Mendapatkan Terapi Bekam. Fakultas Keperawatan Universitas Riau; 2015.

Siregar SK, Peternakan F, Andalas U. Karakterisasi bakteri asam laktat asal susu kerbau dari nagari sianok kabupaten agam. 2019;

Surono IS. Probiotik, mikroorganisme dan pangan fungsional. 2016. 1–209 p.

Saputra M. Pengaruh Pemberian Yoghurt Sinbiotik Tanpa Lemak Dengan Penambahan Tepung Gembili Terhadap Kadar Kolesterol Total Tikus Hiperkolesterolemia. Fakultas Kedokteran Indonesia Program Studi Ilmu Gizi; 2015

Suseno C. Pengaruh Probiotik Dadih Terhadap Kadar Kolesterol Darah Total Pada Tikus Model Hiperkolesterolemia. Fakultas Kedokteran Universitas Andalas; 2017.

Tsail. et al. Pengaruh Ekstrak Propolis Terhadap Kadar TNF-a dan C-Reaktif Protein CPR Studi Eksperimental Pada Tikus Jantan Galur Wistar. Unissula; 2014.

Usmiati S, Broto W & Setiyanto H. Karakteristik Dadih Susu Sapi yang Menggunakan Starter Bakteri Probiotik; 2011. JITV, 16(2), 140–152.

Wulansari V. Faktor-Faktor Yang Berhubungan Hiperkolesterolemia ( Studi Kasus Pada Pegawai Wanita Di Dinas Kesehatan Kota Pontianak). Skripsi Fak Ilmu Kesehat. 2017;1–104.