TINGKAT PENGETAHUAN MAHASISWA PROFESI APOTEKER MENGENAI MODIFIKASI WAKTU MINUM OBAT BERDASARKAN PENDEKATAN KRONOFARMAKOLOGI

Authors

  • Ilham Alifiar Universitas Bakti Tunas Husada Tasikmalaya
  • Nur Rayahuningsih Universitas Bakti Tunas Husada Tasikmalaya
  • Vidya Febrasca Universitas Bakti Tunas Husada Tasikmalaya

Keywords:

Pharmacist, chronopharmacology, circadian rhythm

Abstract

Chronopharmacology is a derivative of pharmacological science that focuses on modifying the time of taking drugs based on the circadian rhythm of the human body for 24 hours. Modification of the time to take this medicine becomes a science that must be mastered by pharmacists to serve the community. This research aims to find out the level of knowledge of students' education pharmacist profession in mastering the science of chronopharmacology. This study is an experimental study conducted on prospective pharmacist students. The research was conducted by giving a questionnaire that contains 10 questions related to chronopharmacology. The results of filling in the answer are divided into three parts of the score, namely a score of 0-4 indicates a low level of knowledge, a score of 5-7 indicates a moderate level of knowledge, while a score of 8-10 indicates a high level of knowledge. In this study, a sample of 49 students was obtained with a sample of 11 men and 36 women. The average overall score of the sample was 5.22 with the highest score of 8 and the lowest score of 2, and the median score of 6. From the data, it can be concluded that the mastery of students related to the science of chronopharmacology is in the medium range.

Downloads

Download data is not yet available.

References

Crnko, S., Du Pré, B. C., Sluijter, J. P. G., & Van Laake, L. W. (2019). Circadian rhythms and the molecular clock in cardiovascular biology and disease. Nature Reviews Cardiology, 16(7), 437–447. https://doi.org/10.1038/s41569-019-0167-4

De Giorgi, A., Fabbian, F., Di Simone, E., Greco, S., De Giorgio, R., Zuliani, G., Passaro, A., Caselli, E., Manfredini, R., Boari, B., Brombo, G., Capatti, E., Cutini, A., Nora, E. D., D’Amuri, A., Ferrocci, G., Vece, F. Di, Fornasari, L., Molino, C., … Caprioli, F. T. (2020). Morning vs. evening administration of antiviral therapy in COVID-19 patients. A preliminary retrospective study in Ferrara, Italy. European Review for Medical and Pharmacological Sciences, 24(15), 8219–8225. https://doi.org/10.26355/eurrev_202008_22511

Khedhaier, W. B. C., Dridi, I., Aouam, K., Ben-Attia, M., Reinberg, A., & Boughattas, N. A. (2017). Circadian variation in anticonvulsant activity of valproic acid in mice. Biomedicine and Pharmacotherapy, 95, 25–30. https://doi.org/10.1016/j.biopha.2017.08.047

Mckinney, W., Yonovitz, A., & Smolensky, M. H. (2015). Circadian variation of gentamicin toxicity in rats. Laryngoscope, 125(7), E252–E256. https://doi.org/10.1002/lary.25116

Prayle, A. P., Jain, K., Touw, D. J., Koch, B. C. P., Knox, A. J., Watson, A., & Smyth, A. R. (2016). The pharmacokinetics and toxicity of morning vs. evening tobramycin dosing for pulmonary exacerbations of cystic fibrosis: A randomised comparison. Journal of Cystic Fibrosis, 15(4), 510–517. https://doi.org/10.1016/j.jcf.2015.07.012

Puspitasari, E. D. (2019). Faktor-faktor yang Mempengaruhi Kesulitan Belajar Mahasiswa Pendidikan Biologi pada Mata Kuliah Kimia Dasar. Seminar Nasional Pendidikan Sains, 2010, 152–161.

Sari Asih, R., Alifiar, I., & Sukmawan, Y. P. (2020). Pengaruh Kronofarmakologi Terhadap Kadar Kolesterol Total Dan Trigliserida Dalam Darah Pasien Pengguna Obat Golongan Statin Dan Fibrat Effects of Chronopharmacology on Total Cholesterol Levels and Triglycerides in Blood Users of Medication I N Statins and. JFL Jurnal Farmasi Lampung, 9(2), 78–84.

Schober, P., & Schwarte, L. A. (2018). Correlation coefficients: Appropriate use and interpretation. Anesthesia and Analgesia, 126(5), 1763–1768. https://doi.org/10.1213/ANE.0000000000002864

Tahara, Y., & Shibata, S. (2014). Chrono-biology, chrono-pharmacology, and chrono-nutrition. Journal of Pharmacological Sciences, 124(3), 320–335. https://doi.org/10.1254/jphs.13R06CR

Zangirolami-Raimundo, J., Echeimberg, J. de O., & Leone, C. (2018). Research methodology topics: Cross-sectional studies. Journal of Human Growth and Development, 28(3), 356–360. https://doi.org/10.7322/jhgd.152198

Downloads

Published

2022-06-02

How to Cite

Alifiar, I. ., Rayahuningsih, N. ., & Febrasca, V. . (2022). TINGKAT PENGETAHUAN MAHASISWA PROFESI APOTEKER MENGENAI MODIFIKASI WAKTU MINUM OBAT BERDASARKAN PENDEKATAN KRONOFARMAKOLOGI. Nusantara Hasana Journal, 2(1), 151–156. Retrieved from https://nusantarahasanajournal.com/index.php/nhj/article/view/326